What are Adhesions (Internal Scar
Tissue)?
Dr. David
Wiseman
An
ADHESION is a type of scar that forms an abnormal
connection between two parts of the body. Adhesions can cause
severe clinical problems. For example, adhesions involving the
female reproductive organs (ovaries, Fallopian tubes) can and do
cause infertility,
dyspareunia (painful
intercourse)and debilitating pelvic
pain. Adhesions
involving the bowelcan
cause bowel
obstructionor blockage.
Adhesions may form elsewhere such as around
the heart,
spine and in the hand where they lead to other
problems.
Adhesions occur
in response to injuryof various kinds.
For example, non surgical insults such as endometriosis, infection,
chemotherapy, radiation and cancer may damage tissue and initiate
ADHESIONS. By far the most common kind of ADHESION is the one that
forms after surgery. ADHESIONS typically occur at the site of a
surgical procedure although they may also occur
elsewhere.
The Magnitude of the Problem of
Adhesions
The
rate of adhesion
formationafter surgery is
surprising given the relative lack of knowledge about ADHESIONS
among doctors and patients alike. From autopsies on victims of
traffic accidents, Weibel and Majno (1973) found that 67% of
patients who had undergone surgery had adhesions. This number
increased to 81% and 93% for patients with major and multiple
procedures respectively. Similarly, Menzies and Ellis (1990) found
that 93% of patients who had undergone at least one previous
abdominal operation had adhesions, compared with only 10.4% of
patients who had never had a previous abdominal operation.
Furthermore, 1% of all laparotomies developed obstruction due to
adhesions within one year of surgery with 3% leading to obstruction
at some time after surgery. Of all cases of small bowel
obstruction, 60-70% of cases involve adhesions (Ellis,
1997).
Lastly, following
surgical treatment of adhesions causing intestinal obstruction,
obstruction due to adhesion reformation occurred in 11 to 21% of
cases (Menzies, 1993).
Between 55
and 100% of patientsundergoing pelvic
reconstructive surgery will form adhesions.
Adhesions and Chronic Pelvic Pain
(CPP)
ADHESIONS are
believed to cause pelvic pain by tethering down organs and tissues,
causing traction (pulling) of nerves. Nerve endings may become
entrapped within a developing adhesion. If the bowel becomes
obstructed, distention will cause pain.
Some patients in
whom chronic pelvic pain has lasted more than six months may
develop "Chronic Pelvic Pain Syndrome." In addition to the chronic
pain, emotional and behavioral changes appear due to the duration
of the pain and its associated stress. According to
the International Pelvic Pain
Society:
"We
have all been taught from infancy to avoid pain. However, when pain
is persistent and there seems to be no remedy, it creates
tremendous tension. Most of us think of pain as being a symptom of
tissue injury. However, in chronic pelvic pain almost always the
tissue injury has ceased but the pain continues. This leads to a
very important distinction between chronic pelvic pain and episodes
of other pain that we might experience during our life: usually
pain is a symptom, but in chronic pelvic pain, pain becomes the
disease."
Chronic pelvic
pain is estimated to affect nearly 15% of women between 18 and 50
(Mathias et al., 1996). Other estimates arrive at between 200,000
and 2 million women in the United States (Paul,
1998). The
economic effects are also quite staggering. In a survey of
households, Mathias et al. (1996) estimated that direct
medical costs for outpatient visits for chronic pelvic pain
for the U.S. population of women aged 18-50 years are $881.5
million per year. Among 548 employed respondents, 15%
reported time lost from paid work and 45% reported reduced
work productivity.
Not all ADHESIONS
cause pain, and not all pain is caused by
ADHESIONS.
Not all surgeons,
particularly general surgeons, agree that ADHESIONS cause pain. Part of the
problem seems to be that it is not easy to observe ADHESIONS non
invasively, for example with MRI or CT scans. However, several
studies do describe the relationship between pain and
adhesions. According to an
early study (Rosenthal et al., 1984) of patients reporting CPP,
about 40% have adhesions only, and another 17% have endometriosis
(with or without adhesions). Kresch et al., (1984) also studied 100
women and found ADHESIONS in 38% of the cases and endometriosis in
another 32%.
Overall estimates (Howard, 1993) of the percentage of patients with
CPP and ADHESIONS is about 25%, with endometriosis accounting for
another 28%. These figures must be understood in their context, and
I recommend highly Howard's article.
It is important to
recognize that emotional stress contributes greatly to the patients
perception of pain and her/his ability to deal with the pain.
Rosenthal et al. (1984) found that of the patients in whom a
possible physical cause of pain (including ADHESIONS) could be
identified, 75% had evidence of psychological influences on the
pain.
Conclusion: You Are Not
Alone
Adhesions are almost an inevitable outcome of surgery, and the
problems that they cause are widespread and sometimes severe. It
has been said by some that adhesions are the single most common and
costly problem related to surgery, and yet most people have not
even heard the term. This lack of awareness means that many doctors
are unable or unwilling to tackle the problems of adhesions, many
insurance companies are unwilling to pay for treatment and many
patients are left in misery.
We are witnessing the beginning of a reversal of this situation as
can be seen from a recent
conferenceon pelvic
pain.
If you are
suffering from the effects of adhesions, I hope that you have
learned that YOU ARE NOT ALONE Emotional stress plays a major role
in the pain that ADHESIONS can cause. A good support network is
essential and "a trouble shared is a trouble halved." Many patients
have reported that by sharing their experiences with others, be it
by phone, local support group or the Internet, their feelings of
loneliness, abandonment and frustration have abated, engendering a
healing frame of mind.
I have had a
number of requests to start a patient support group for ADHESIONS
sufferers (suggested motto: Let's Stick Together!!) whose goals
would be:
to
share experiences and information
to
provide support and advice to is members
to
raise the level of awareness among doctors, health care providers,
government, prompting them to provide more comprehensive and
integrated care for adhesions sufferers
to
support scientific research into adhesions and their
prevention
©
1998 SYNECHION, INC.
Please note that this article is not intended to provide
specific medical advice. In all cases, an appropriately qualified
medical doctor should be consulted about your condition and your
proper treatment.
Chronic pelvic
pain and/or associated intestinal disturbance are a major cause of
misery for thousands of patients. Often in constant pain, the
patient experiences loneliness, hopelessness, frustration and
desperation with thoughts of suicide. Family and work relationships
are strained to the limit. Although ADHESIONS are often (but not
always) the cause of this pain, treatment for adhesions is not
performed either because the surgeon does not believe that
adhesions can cause the problem, or because lysis of adhesions is
considered too difficult or futile.
Adhesions are an almost inevitable outcome of surgery,
and the problems that they cause are widespread and sometimes
severe. It has been said by some that adhesions are the single most
common and costly problem related to surgery, and yet most people
have not even heard the term. This lack of awareness means that,
excluding infertility, many doctors are unable or unwilling to
tackle the problems of adhesions, many insurance companies are
unwilling to pay for treatment and many patients are left in
misery.
This
paper describes adhesions, their treatment and their relationship
to pain and bowel obstruction. In addition, stories from patients
are featured to illustrate how adhesions (or suspected adhesions)
affect their daily lives and how they cope with a sometimes
insurmountable problem.
A
key lesson and source of comfort for patients with this problem is
that they are not alone and the importance of mutual support among
patients cannot be underestimated.
There are no easy answers as yet. In drawing attention
to the human side of this problem, we hope to (begin to) educate
patients and doctors about the range of treatments available, be
they of a medical, surgical or psychological nature. In addition,
the establishment of a group to provide support and information to
adhesions sufferers is proposed.
Abdominal
Adhesions
Written by Dr. Harry Reich
http://www.womenssurgerygroup.com/physicians/HarryReichCV.asp#_Toc26028977
Adhesions are
abnormal, scar-like, fibrous tissue bands that develop after
surgery between separate tissues, organs and structures in the
body. They are sometimes known as intrauterine, pelvic or
pericardial adhesions.
Adhesions may be the result of an episode of pelvic inflammatory
disease or endometriosis, but most commonly are caused by previous
pelvic and abdominal surgery. Adhesions cause pain through
entrapment of the organs they surround, as well as disrupt bowel
function, or cause infertility. The surgical management of
extensive pelvic adhesions is one of the most difficult problems
facing surgeons today.Data suggests 67 to 93 percent of abdominal
surgery patients will develop the condition following surgery,
while 55 to 100 percent of gynecologic surgery patients will
develop them.
De novo are new
adhesions that may form at a site of direct surgical trauma such as
an incision. They may also develop at locations away from the site
of surgery, for example, around the adnexa at the time of a
cesarean section. Adhesions may also reform following adhesiolysis
or adhesiectomy.
Three greater
types of adhesions exist, but the underlying pathophysiology is
similar for each:
Filmy
Vascular
Cohesive
A better
scientific understanding of peritoneum and its response to injury
is important in understanding how we might prevent adhesion
formation. The peritoneum is a strong, colorless membrane that
lines the abdomino-pelvic walls and forms a double-layered sac
continuous with the mucous membrane of the uterine tubes in the
female. The space between the parietal and visceral peritoneum is
called the peritoneal cavity. The peritoneum is composed of
multiple layers, that respond to injury through inflammation. This
result is inevitable during surgery. The process occurs over 1 to 7
days. Over the next several months, changes continue characterized
by the adhesions becoming more dense.
There is evidence that the use of physical barriers between tissues
may reduce the incidence of adhesions. Barriers have included
gauze, minimally moistened dry sponges, Intercede by Johnson and
Johnson Medical, Inc., a Gore-Tex surgical membrane composed of
expanded polytetrafluoroethylene, and Seprafilm.1 Steroids and
other liquid and pharmacological agents to prevent post-operative
adhesions may be beneficial, but more research needs to be
conducted.2 Antihistamines, corticosteroids, and nonsteroidal
anti-inflammatory drugs have been used. Efforts are currently
underway to use a promising new hyaluronic acid-based gel, which is
being evaluated in a multicenter randomized trial to determine its
safety and effectiveness. One established standard-of-care that has
been widely adopted includes the administration of a steroid along
with an antihistamine. Frequent irrigation of tissues is also
recommended to keep tissues moist and limit tissue
desiccation.Minimally invasive surgery, along with microsurgical
techniques, lead towards less tissue destruction during surgery. It
may be possible, therefore, for less of a chance of adhesions
developing. However, studies have shown that adhesion rates in
patients undergoing laparotomy may be between 70 and 90 percent. So
in order to minimize the chances of adhesion formation, trauma
should be minimized, tissues hydrated, less-restrictive sutures
used, and good bleeding control applied. Other investigators have
observed a 70 percent incidence in patients with previous
gynecologic surgery, 50 percent incidence with previous
appendectomy and even a more than a 20 percent incidence in
patients with no surgical history. Other studies continue with
special attention being paid to the incidence of de novo adhesion
formation in laparotomy and laparoscopy
The Chemical
Process That Leads To Adhesions
During
the body's reaction that leads to an adhesion, chemicals called
inflammatory mediators and histamines are released from the blood
(more specifically the blood's mast cells and leukocytes).
Capillaries dilate. This allows leukocytes, red blood cells and
platelets to concentrate at the injury site in a bundle called a
fibrinous exudate. A variety of other factors are at play in the
system such as asprostaglandins, bradykinin, chemotactic agents,
lymphokines, seretonin and transforming growth factor.
At this point in time fibrinolysis may clear the fibrinousexudate.
In order for this to occur, plasminogen must be converted to
plasmin by tissue plasminogen activator (t-PA). There is constant
play between the t-PA and plasminogen-activator inhibitors.
Unfortunately surgical trauma normally decreases t-PA activity
while simultaneously increasing plasminogen activator inhibitors.
If this occurs, the fibrinous exudate is transformed into an
organized adhesion where fibers of collagen are deposited. Blood
vessels begin to form, which leads to an
adhesion.
What Are the Symptoms of
Adhesions?
Symptoms vary depending on the tissues involved. For example, in
the gastrointestinal tract, bowel obstructions may occur. In the
uterus, adhesions can cause ... In the pelvis, adhesions can cause
infertility and other reproductive problems.
Clinically, adhesions present as fever, chronic or acute abdominal,
pelvic or chest pain, partial or complete mechanical bowel
obstruction, and infertility. Mechanical small bowel obstruction
after previous surgery can be the most severe effect of adhesions.
Historical
Understanding, Causes & Frequency Data
During 1988 there were 281,982 hospitalizations during which
adhesiolysis (the cutting, ablation or division of adhesions) was
performed in the United States, accounting for 948,727 days of
inpatient care. Of the admissions, 54,100 were precipitated by
adhesions. At the time, these hospitalizations were responsible for
an estimated $1,179,900 in healthcare expenditures. This estimate
does not include outpatient surgical procedures.
Intra-abdominal adhesions are usually the
result of surgical or gynecologic operations, pelvic inflammatory
disease (gonococcal or chlamydial), appendicitis or endometriosis.
Adhesions occur after abdominal surgery in more than 60 percent of
cases, though less than 30 percent are
symptomatic.
Adhesions may be
responsible for chronic persistent abdominal pain without
associated pelvic pathology. Clinically, adhesions present as
chronic or acute abdominal or pelvic pain, partial or complete
mechanical bowel obstruction, and infertility. Though adhesions
probably cause pain by entrapment of expansile viscera, the
relationship of adhesions to abdominal pain is still controversial.
In contrast, mechanical small bowel obstruction after previous
surgery demonstrates unequivocally the most severe effect of
adhesions.
Patients with chronic or recurrent abdominal pain and a
history of numerous abdominal surgical procedures are often denied
treatment if they are not obstructed or symptomatic of intermittent
bowel obstruction. This may be because, from the surgeon's
viewpoint, adhesiolysis is associated with low reimbursement for
long operations with high medicolegal risk. Also, adhesions may
recur, and the risk of enterotomy (a hole in the bowel) during
surgery is very high.
While surgical therapy is withheld, multiple abdominal
diagnostic procedures including abdominal CT scan are frequently
ordered. The patients are then sent to chronic pain clinics for
evaluation. Though few studies exist, a recent report suggests that
women with severe, dense vascularized bowel adhesions have a
significant reduction in pain after
adhesiolysis.
A
View From the Inside Out... Dr. Harry Reich is
the most skilled laparascopic surgeons develop ambidextrous
surgical skills in order to maneuver the various cutting, sewing,
laser and visualization (endoscopic mini-video cameras) tools
required in minimally invasive laparoscopic surgery. Here, Dr.
Reich views a patient's pathology on a TV screen while manipulating
two surgical tools from outside the patient's body. The tools fit
through ports in the patient's skin. Copyright © Harry
Reich.
Minimally Invasive
Treatments
No longer can the public ignore the benefits of minimally invasive
surgery for adhesions. While these techniques and procedures are
not without risk, patients should not be denied the procedures'
inherent advantages. Astute clinicians must work together to
discern the most appropriate uses and cases for this therapy.
Patients with symptomatic adhesions usually want minimally invasive
therapy. If given the choice between a laparoscopic surgical
procedure and laparotomy, they will rarely choose the latter.
Unfortunately this choice is seldom offered, even though most
adhesiolysis laparotomy procedures presently performed can be done
through the laparoscope.
While the
advantages of laparoscopic enterolysis compared with classical
laparotomy has not been proven in studies, it is obviously possible
with laparoscopy to diminish peritoneal mesothelial cell ischemic
damage from trauma, drying, talc, packs and delayed bleeding.
Laparoscopic surgery is distinctly advantageous as the preferred
method of access for infertility surgery due to the decreased risk
of de novo adhesion formation. Similar surgical outcomes when
compared to laparotomy have been demonstrated in the management of
endometriosis and extensive adhesions. The surgical advantages of
laparoscopy include panoramic pelvic visualization and
magnification, techniques similar to microsurgery, documentation of
absolute hemostasis via underwater examination.
Finally, the patient enjoys simultaneous diagnosis and treatment
and all the advantages of minimally invasive surgery in terms of
cosmetics and rapid recuperation. Ileus is rare after laparoscopic
surgery. In 2000, the onus should be on the surgeon to prove that
laparotomy results in better outcome than laparoscopy, not
vice-versa.
Laparascopic Peritoneal Cavity
Adhesiolysis
Although both laparoscopic and laparotomy adhesiolysis can be very
time-consuming (2 to 4 hours), and for the surgeon technically
difficult, many women are discharged on the same day of the
procedure, avoid major abdominal incisions, experience minimal
complications and return to full activity within one week of the
procedure. The extent, thickness and vascularity of adhesions
varies widely. Intricate adhesive patterns exist with fusion to
parietal peritoneum and/or various meshes.
Peritoneal adhesiolysis is classified into enterolysis, which
includes omentolysis and female reproductive reconstruction
(salpingo-ovariolysis and cul-de-sac dissection with excision of
deep fibrotic endometriosis).
Bowel adhesions are divided into:
* Upper Abdominal
* Lower Abdominal
* Pelvic
* Combinations of the Above
Adhesions
surrounding the umbilicus are upper abdominal as they require an
upper abdominal laparoscopic view for division.
Extensive small bowel adhesions are not a frequent finding at
laparoscopy for pelvic pain or infertility. In these cases, either
the tube is stuck to the ovary or the ovary is adhered to the
pelvic sidewall. The rectosigmoid (the rectum and sigmoid colon)
may cover both. Rarely, the omentum (a fold of peritoneum extending
from the stomach to adjacent organs in the abdominal cavity) and
small bowel are involved.
On a side note, we are working on a classification system for
extensive peritoneal cavity adhesion procedures that relates to
their degree of severity and expertise necessary for adhesiolysis.
For now, the single best indicator of the degree of severity and
expertise necessary for adhesiolysis is the number of previous
laparotomies. The frequency of small bowel obstruction symptoms
also indicates the need for surgery
(TOP)
Typical Surgical Plan for Extensive
Enterolysis
A well defined strategy is important for small bowel enterolysis.
In general, cases are divided into three parts:
1.) Division
of all adhesions to the anterior abdominal wall parietal
peritoneum. Small bowel loops encountered during this process are
separated using their anterior attachment for countertraction
instead of waiting until the last portion of the procedure (running
of the bowel).
2.)Division
of all small bowel and omental adhesions in the pelvis. The
rectosigmoid, cecum and appendix often require some separation
during this part of the procedure.
3.)Running
of the bowel. Using atraumatic grasping forceps and (usually) a
suction irrigator for suction traction, the bowel is run. Starting
at the cecum and terminal ileum, loops and significant kinks are
freed into the high-upper abdomen to the ligament of
Treitz.
4.)Optional.
Tubo-ovarian pathology is then treated if indicated.
Time frequently dictates that all adhesions cannot be lysed. From
the history, the surgeon should conceptualize the adhesions most
likely to be causing the pain, i.e., upper or lower abdomen, left
or right, and clear these areas of adhesions.
With minimally invasive surgical approaches, same-day discharge is
common, even after long procedures. Physical motility of the bowel
is encouraged by early ambulation and a clear liquid diet for 2 to
4 days. Patients are instructed to return gradually to their normal
activity during the week after surgery.
Partial small-bowel obstruction during the week after surgery is
usually due to ileus and is treated by intravenous hydration and a
nasogastric tube if vomiting is present. Surgical exploration
should be avoided in these cases.
If peritonitis occurs in the days after the operation, it must be
assumed that an injury to the bowel has gone unnoticed and a
laparotomy is indicated. If an abscess forms postoperatively it can
be drained percutaneously under sonographic guidance, or possibly
by means of a laparoscopy. Recurrent adhesions may occur even with
atraumatic techniques. Despite refinement in operative technique
and the recent introduction of adhesion-prevention products, the
problem of postoperative adhesions remains a major cause of
infertility and pain. All surgeons must deal with the potential for
formation of adhesions after surgery, as well as the sequelae of
adhesions from previous surgery which may markedly increase the
difficulty of any particular surgerical case.
Post-surgical adhesions often occur following pelvic and abdominal
surgery. Data has suggested that 67% to 93% of patients will
develop adhesions following non-gynecologic abdominal surgery and
55% to 100% of patients will develop adhesions following
gynecologic surgery. These issues become critically important from
a standpoint of reproductive potential.Additionally, adhesions may
be associated with issues such as pelvic pain, abnormalities of
bowel function, and small bowel
obstruction.
Women's Surgery Group on Adhesions
http://www.womenssurgerygroup.com
Definitions
Several definitions of adhesions exist. De novo or new adhesions
may form at a site where none existed before but a surgical
procedure was performed. Examples include a myomectomy incision or
an ovarian incision at the time of ovarian cystectomy. De novo
adhesions may also develop away from the site of surgery,such as
adhesions developing around the tubes and ovaries at the time of a
cesarean section. Adhesions may also reform following adhesiolysis
or adhesiectomy.
Three general types of adhesions exist - filmy, vascular, and
cohesive. The underlying pathophysiology of all three, however,is
similar. The American Fertility Society has attempted to classify
adhesive disease according to the location and type of
adhesions.
The Peritoneum
An understanding of the anatomy of the peritoneum and the response
of the peritoneum to injury is important in understanding how we
might prevent adhesion formation. The peritoneum is composed of
multiple layers. The mesothelium is the innermost layer, a layer of
connective tissue which contains the blood vessels, and a basement
membrane. When the peritoneum is injured (which is inevitable
during surgery), there is an inflammatory response.
During the initial phase of this inflammatory response,
inflammatory mediators and histamine are released from mast cells
and leukocytes. Capillaries located within the connective tissue
dilate and an increased permeability of the capillary wall is
noted. This allows leukocytes, red blood cells and platelets to
become concentrated at the site of in injury. A fibrinous exudate
is thus formed at the site of injury. Multiple factors such as
prostaglandins, lymphokines, bradykinin, serotonin, transforming
growth factor and other chemotactic agents are present within the
exudated material.
At this point the fibrinous exudate may be cleared through
fibrinolysis. In order for this to occur, plasminogen must be
converted to plasmin by tissue plasminogen activator (t-PA).There
is a constant balance in the system between tissue plasminogen
activator and plasminogen activator inhibitors. Unfortunately,
surgical trauma may have an inherent ability to decrease tissue
plasminogen activity while increasing plasminogen activator
inhibitors. Under normal circumstances plasmin breaks down exudated
fibrin. If this does not occur, the fibrinous exudate is converted
into an organized adhesion and fibers of collagen are deposited.
Following this, blood vessels begin to form allowing organization
of the adhesion.
This process occurs over a one to seven day period of time. In
general, at seven days the quantitative development of adhesions is
complete. Qualitative changes continue over the next several months
with adhesions becoming more dense and
vascularized.
Author: Eugene
Hardin, MD, Chair, Department of Emergency Medicine, Martin Luther
King Jr/Charles R Drew Medical Center; Medical Director, Hubert H
Humphrey Comprehensive Health Center
Coauthor(s): Christopher R Westfall, DO, Staff Physician,
Department of Emergency Medicine, Kern Medical Center
Editor(s): Scott H Plantz, MD, FAAEM, Research Director, Assistant
Professor, Department of Emergency Medicine, Mount Sinai School of
Medicine; Francisco Talavera, PharmD, PhD, Senior Pharmacy Editor,
eMedicine; Carmelito (Sonny) Arkangel, Jr, MD, Assistant Professor,
Department of Surgery, Division of Emergency Medicine, University
of Texas Health Science Center at San Antonio; Jonathan Adler, MD,
Instructor, Department of Emergency Medicine, Massachusetts General
Hospital, Harvard Medical School; and Anthony Anker, MD, Consulting
Staff, Department of Emergency Department, Rogue Valley Medical
Center
An adhesion
is:
· A band of scar tissue that binds 2 parts of your tissue
together. They should remain separate. Adhesions may appear as thin
sheets of tissue similar to plastic wrap, or as thick fibrous
bands.
· The tissue develops when the body's repair mechanisms
respond to any tissue disturbance, such as surgery, infection,
trauma, or radiation. Although adhesions can occur anywhere, the
most common locations are within the stomach, the pelvis, and the
heart.
· Abdominal adhesions: These are a common complication of
surgery, occurring in up to 93% of people who undergo abdominal or
pelvic surgery. Adhesions also occur in 10.4% of people who have
never had surgery.
· Most adhesions are painless and do not cause complications.
However, adhesions cause 60%-70% of small bowel
· Obstructions in adults and are believed to contribute to the
development of chronic pelvic pain.
· Adhesions typically begin to form within the first few days
after surgery, but they may not produce symptoms for months or even
years. As scar tissue begins to restrict motion of the small
intestines, passing food through the digestive system becomes
progressively more difficult. The bowel may become blocked.
· In extreme cases, adhesions may form fibrous bands around a
segment of an intestine. This constricts blood flow and leads to
tissue death.
· Pelvic adhesions: These may involve any organ within the
pelvis, such as the uterus, ovaries, fallopian tubes, or bladder,
and usually occur after surgery. Pelvic inflammatory disease (PID)
results from an infection (usually a sexually transmitted disease)
that frequently leads to adhesions within the fallopian tubes. A
woman's eggs pass through her fallopian tubes into her uterus for
reproduction. Fallopian adhesions can lead to infertility and
increased incidence of ectopic pregnancy in which a fetus develops
outside the uterus.
· Heart adhesions: Scar tissue may form within the membranes
that surround the heart (pericardial sac), thus restricting heart
function. Infections, such as rheumatic fever, may lead to
adhesions forming on heart valves and leading to decreased heart
efficiency.
When the body
attempts to repair itself, adhesions develop. This normal response
can occur after surgery, infection, trauma, or radiation. Repair
cells within the body cannot tell the difference between one organ
and another. If an organ undergoes repair and comes into contact
with another part of itself, or another organ, scar tissue may form
to connect the 2 surfaces.
Signs and symptoms NS AND SYMPTOMS
Doctors associate signs and symptoms of adhesions with the problems
an adhesion causes rather than from an adhesion directly. As a
result, people experience many complaints based on where an
adhesion forms and what it may disrupt. Typically, adhesions show
no symptoms and go undiagnosed.
Most commonly, adhesions cause pain by pulling nerves, either
within an organ tied down by an adhesion or within the adhesion
itself.
· Adhesions above the liver may cause pain with deep
breathing.
· Intestinal adhesions may cause pain due to obstruction
during exercise or when stretching.
· Adhesions involving the vagina or uterus may cause pain
during intercourse.
· Pericardial adhesions may cause chest pain.
· It is important to note that not all pain is caused by
adhesions and not all adhesions cause pain.
· Small bowel obstruction (intestinal blockage) due to
adhesions is a surgical emergency.
.These adhesions trigger waves of cramp like pain in your stomach.
This pain, which can last seconds to minutes, often worsens if you
eat food, which increases activity of the intestines.
Once the pain starts, you may vomit. This often relieves the
pain.
· Your stomach may become tender and progressively
bloated.
· You may hear high-pitched tinkling bowel sounds over your
stomach, accompanied by increased gas and loose stools.
· Fever is usually minimal.
· Such intestinal blockage can correct itself. However, you
must see your doctor. If the blockage progresses, these conditions
may develop:
· Your bowel stretches further.
· Pain becomes constant and severe.
· Bowel sounds disappear.
· Gas and bowel movements stop.
· Your belly will grow.
· Fever may increase.
· Further progression can tear your intestinal wall and
contaminate your abdominal cavity with bowel contents.
See a doctor any time you experience abdominal pain, pelvic pain,
chest pain, or unexplained fever. If you have undergone surgery or
have a history of medical illness, discuss any changes in your
recovery or condition with your doctor.
Go to the nearest Emergency Department if chest
pain, abdominal pain, pelvic pain, or unexplained fever
occurs.
Doctors typically diagnose
adhesions during a surgical procedure such as laparoscopy (putting
a camera through a small hole into the stomach to visualize the
organs). If they find adhesions, doctors usually can release them
during the same surgery.
Studies such as blood tests, x-rays, and CT scans might be useful
to determine the extent of an adhesion-related problem. However, a
diagnosis of adhesions is made only during surgery. A physician,
for example, can diagnose small bowel obstruction but cannot
determine if adhesions are the cause without surgery.
Treatment varies depending on the location, extent of adhesion
formation, and problems the adhesion is causing. Adhesions
requiring surgery commonly come back because surgery itself causes
adhesions. Unless a surgical emergency becomes evident, a doctor
may treat symptoms rather than perform surgery.
A common surgical techniques used to diagnose abdominal adhesions
ia a laparoscopy but many of these surgeries result in a
laparotomy.
· With laparoscopy, a doctor places a camera into your body
through a small hole in the skin to confirm that adhesions exist.
The adhesions then are cut and released (adhesiolysis).
· In laparotomy, a doctor makes a larger incision to directly
see adhesions and treat them. The technique varies depending on
specific circumstances.
Several surgical products have been developed to prevent adhesions
from forming during surgery. However, the effectiveness of these
products is debatable.